SLU-PP-332 Peptide

Price range: €141.04 through €278.04

Technical Specifications

Specification	Detail
Product Name	SLU-PP-332 Peptide (ERR Agonist)
Quantity	5mg per vial
Purity	≥99% (HPLC verified)
Form	Lyophilized powder
Appearance	White to off-white lyophilized powder
Molecular Weight	482.96 g/mol
CAS Number	2766700-43-8
Molecular Formula	C₂₅H₂₇ClN₄O₄
Target Receptors	ERRα, ERRβ, ERRγ
EC₅₀ (ERRα)	~20-50 nM
Solubility	DMSO ≥10 mg/mL; limited water solubility
Key Research Areas	Exercise mimetics, metabolic disease, mitochondrial function, cardiovascular research, muscle biology
Storage (Lyophilized)	-20°C; protect from light and moisture
Storage (Reconstituted)	2-8°C for short-term; aliquot and store at -20°C for longer storage
Shelf Life	24 months from manufacture date (lyophilized)
Shipping	Ambient temperature with protective packaging
Intended Use	Research and laboratory use only
Documentation	Certificate of Analysis provided with each batch

SKU: N/A Category: Buy Peptide Online UK Tags: ≥99% purity, 48 hour delivery, 48 hour delivery peptide, Academic discount, academic lab, academic research, accelerated stability, ADME, ADME screening, aging research, AMPK activation, AMPK Pathway, analytical method development, animal study, application note, application support, applied research, Aseptic technique, assay development, ATP production, atrophy prevention, audit trail, authority, basic research, batch release, batch tested, binding affinity, bioavailability, bioavailability improvement, Biochemical Assays, bioenergetics, Biomarker discovery, biotechnology, Biotechnology company, biotechnology research, brand awareness, brand loyalty, brown adipose tissue, bulk ordering, bundle deal, buy peptide online EU, buy peptide online UK, buy SLU-PP-332 EU, buy SLU-PP-332 UK, C25H27ClN4O4, C2C12 myotubes, cachexia, calorie restriction, calorie restriction mimetic, cardiac metabolism, cardiometabolic, cardiometabolic research, Cardiovascular research, CART, CAS 2766700-43-8, case study, category page, cell based assays, cell culture, cellular energetics, cellular respiration, Certificate of Analysis, characterization, checkout, Chemical synthesis, citation database, clearance, Clinical research, clinical translation, clinical trial, CoA, cold chain, collaboration, college, combo offer, commercial buyer, commercialization, community, competitive analysis, computational chemistry, confidentiality agreement, consistency, content marketing, contract manufacturing, contract research organization, controlled substances, conversion optimization, corporate citizenship, cost analysis, credibility, CRO, custom synthesis, customer acquisition, customer feedback, customer retention, customer service, Customer support, Customer testimonial, Customs clearance, damage claim, data integrity, Data protection, defective product, Delivery confirmation, diabetes research, Diet induced obesity, discount code, discovery research, discussion group, dispatch notification, distributor program, DMSO solubility, documentation, Dose escalation, Dose response, dosing protocols, drug development, Drug discovery, drug-drug interactions, ecommerce platform, educational resource, educational use, efficacy biomarkers, efficacy screening, efficacy studies, electron transport chain, elemental analysis, email marketing, Email support, Endotoxin testing, endurance capacity, Endurance Research, endurance training, Energy balance, energy expenditure, environmental stewardship, ERR agonist, ERR agonist research, ERR signaling, ERRα, ERRα agonist, ERRβ, ERRβ agonist, ERRγ, ERRγ agonist, estrogen-related receptor agonist, ethics, EU peptide supplier, eupeptidelap, eupeptidelap peptide, exchange policy, exercise adaptation, exercise capacity, Exercise mimetic, exercise mimetic compound, exercise mimetic research, Exercise physiology, exercise science, Exercise training, experimental compound, experimental design, expertise, export compliance, express shipping, FAQ, fast twitch, fast-twitch muscle, Fatty acid oxidation, fatty acid oxidation pathway, fatty acid synthesis, fiber type switching, forced degradation, formulation development, forum, fragment-based drug design, free shipping, FTIR spectroscopy, functional assays, GC-MS method, GDPR compliance, glucose homeostasis, glucose metabolism, glucose transporter, glucose uptake, GLUT4, GMP compliance, GMP grade, government lab, handling guidelines, healthspan, heavy metal analysis, high purity, high-throughput screening, Hit identification, hit-to-lead, hospital, HPLC method, HPLC Purity, import duties, impurity profiling, in vitro ADME, in vitro research, in vivo PK, in vivo research, IND enabling, IND filing, indirect calorimetry, Industry leader, innovation, Institutional buyer, institutional pricing, insulin receptor, Insulin sensitivity, Insulin signaling, insurance claim, integrity, intellectual property, international shipping, investigational compound, invoice, ISO certification, isothermal titration calorimetry, journal reference, ketone bodies, keyword research, laboratory reagent, laboratory supplies, laboratory use, laboratory use only, lactate metabolism, LC-MS method, lead compound, lead discovery, lead optimization, licensing, licensing agreement, lifespan, Lipid metabolism, literature search, Live chat, logistics, long-term stability, longevity pathway, Longevity research, loyalty program, luciferase assay, lyophilized powder, manufacturing, market approval, market entry, Market leader, market research, Mass spectrometry, material transfer agreement, Maximum tolerated dose, Mechanism of action, mechanism-based screening, medical center, medicinal chemistry, melting point determination, Metabolic adaptation, metabolic biology, metabolic biomarkers, metabolic disease, metabolic disease research, metabolic disorder, metabolic flexibility, metabolic gene expression, Metabolic health, metabolic healthspan, metabolic pathway, metabolic phenotyping, metabolic research, metabolic stability, metabolic syndrome, metabolite identification, method validation, microbial testing, mitochondrial biogenesis, mitochondrial biogenesis pathway, mitochondrial density, mitochondrial disease, mitochondrial function, mitochondrial medicine, mitochondrial pathway, molecular modeling, molecular weight 482.96, mouse model, mTOR pathway, muscle hypertrophy, muscle remodeling, Muscle wasting, NAD+, NDA filing, networking, newsletter, next day delivery, next day delivery peptide, NMR spectroscopy, NOAEL, non-disclosure agreement, non-profit organization, Not for human consumption, nuclear receptor, nuclear receptor agonist, nuclear receptor signaling, obesity research, obesity therapy, off-target screening, online ordering, optimization, oral presentation, Order confirmation, order tracking, organic traffic, oxidative fibers, oxidative metabolism, oxidative muscle fibers, oxidative phosphorylation, oxidative stress, oxygen consumption, partnership, patent application, payment gateway, payment processing, peer-reviewed article, Peptide Albania, Peptide Andorra, peptide characterization, Peptide Cyprus, Peptide Czechia, peptide for sale EU, peptide for sale UK, Peptide Hungary, Peptide Iceland, peptide Ireland, Peptide Kosovo, Peptide Monaco, Peptide Seoul, Peptide Serbia, Peptide Slovenia, Peptide Spain, peptide synthesis, Peptide today, Peptide US, Peptide USA, peptide world, PGC-1α activator, Pharmaceutical company, pharmaceutical research, Pharmacodynamics, pharmacodynamics markers, pharmacokinetic profile, pharmacokinetics, Phase 1, phase 2, phase 3, Phenotypic screening, Phone support, Physical activity, physiology research, PK screening, Plasma half-life, poster presentation, preclinical development, preclinical research, preclinical safety, Pricing strategy, primary myocytes, priority shipping, Privacy policy, process chemistry, product catalog, product insert, product launch, product page, product rating, product review, product warranty, professional use, profiling, profit margin, prohibited items, promotional offer, Protein synthesis, protocol manual, protocol optimization, Pyruvate Dehydrogenase, qualified purchaser, quality, quality assurance, quality control, receipt, redox biology, reference standards, referral program, Refund policy, regulatory compliance, regulatory toxicology, reliability, Replacement policy, reporter gene assays, reputation management, RER, Research collaboration, Research compound, research consultation, research facility, research foundation, Research grade, research institute, research peptide EU, research peptide UK, research reagents, research summary, research tools, research use only, residual solvent analysis, Respiratory exchange ratio, responsibility, restricted substances, Return policy, revenue generation, review system, Rodent model, running endurance, RUO, safety data sheet, safety margin, Safety pharmacology, safety screening, sales growth, SAR, sarcopenia, Satisfaction guarantee, scale up, scientific conference, scientific equipment, scientific publication, screening, SDS, search engine ranking, seasonal sale, secure shipping, Sedentary lifestyle, sedentary model, selectivity screening, seminar, SEO optimization, shipping calculation, shipping damage, shipping policy, SIRT1, skeletal muscle, skeletal muscle research, slow twitch, slow-twitch muscle, SLU-PP-332, SLU-PP-332 for sale EU, SLU-PP-332 for sale UK, small molecule, small molecule agonist, social media, social responsibility, Solubility enhancement, solution preparation, sports science, stability testing, star rating, sterility testing, storage conditions, structural biology, structure-activity relationship, Substrate utilization, supply chain management, surface plasmon resonance, sustainability, symposium, target discovery, target engagement, Target validation, target-based screening, tax calculation, TCA cycle, technical documentation, Technical support, technology transfer, temperature monitoring, Terms of service, therapeutic index, therapeutic window, Thermogenesis, thought leadership, tissue distribution, toxicity studies, Toxicology, Toxicology screening, tracking information, trade regulations, training video, transcription factor assay, transcriptional regulation, Translational medicine, Translational research, transparency, trust building, type I fibers, type II fibers, UK peptide vendor, university, UPLC method, user account, user experience, user guide, uv vis spectroscopy, validation, virtual screening, Volume pricing, webinar, website analytics, website security, Weight management, Wholesale pricing, workshop, X-ray crystallography

Premium SLU-PP-332 Research Compound for Sale | 5mg Lyophilized Powder | ≥99% Purity | 48-Hour Delivery Across EU & UK

SLU-PP-332: The Advanced ERR Agonist for Next-Generation Metabolic Research

Buy SLU-PP-332 Peptide EU & UK, Eupharmaceutical is proud to present SLU-PP-332 Peptide, a premium research-grade small molecule compound manufactured to the highest analytical standards. As a trusted peptide vendor uk and leading EU peptide supplier, we provide researchers across Europe with SLU-PP-332 for sale that delivers exceptional purity, consistency, and documented quality for advanced studies in metabolic regulation, exercise physiology, and mitochondrial biogenesis. Buy SLU-PP-332 Peptide EU & UK

SLU-PP-332 is a synthetic small molecule agonist of the estrogen-related receptors (ERRs), a family of nuclear receptors that play a fundamental role in regulating cellular energy metabolism . Discovered through a structure-based drug design approach, SLU-PP-332 has emerged as one of the most promising research compounds for studying metabolic pathways involved in endurance, energy expenditure, and muscle adaptation .

SLU-PP-332 functions by selectively activating all three estrogen-related receptor isoforms: ERRα, ERRβ, and ERRγ . These receptors are master regulators of metabolic gene expression, controlling pathways involved in:

Mitochondrial biogenesis and oxidative phosphorylation
Fatty acid oxidation and lipid metabolism
Glucose homeostasis and insulin sensitivity
Exercise adaptation and muscle fiber remodeling

A landmark study published in Science demonstrated that SLU-PP-332 treatment in obese mice significantly increased energy expenditure, enhanced fatty acid oxidation, and prevented weight gain . The compound has been shown to increase exercise capacity in animal models without the need for physical training, establishing it as a powerful tool for investigating exercise mimetic pathways .

For researchers seeking to buy peptide online EU for investigations into metabolic disorders, exercise physiology, or mitochondrial function, Eupharmaceutical offers this premium research compound with comprehensive documentation, including Certificates of Analysis and batch-specific purity data. Whether your laboratory is based in London, Berlin, Paris, or anywhere in the European Union, our guaranteed 48 hour delivery peptide service ensures your research continues without interruption.

The Scientific Foundation of SLU-PP-332 Research

Discovery and Development

SLU-PP-332 was identified through a structure-based drug design campaign targeting the estrogen-related receptors (ERRs), a family of orphan nuclear receptors . Unlike traditional nuclear receptors that require specific ligands for activation, ERRs were initially considered “orphan” receptors with no known endogenous ligands. The development of synthetic agonists like SLU-PP-332 has enabled researchers to probe the functional roles of these receptors in metabolic regulation .

Mechanism of Action: Estrogen-Related Receptor Activation

SLU-PP-332 exerts its effects through selective activation of ERRα, ERRβ, and ERRγ . These receptors are constitutively active and function as master transcriptional regulators of genes involved in cellular energy metabolism.

ERRα (Estrogen-Related Receptor Alpha): The most extensively studied ERR isoform, ERRα is highly expressed in tissues with high energy demands, including heart, skeletal muscle, brown adipose tissue, and kidney . ERRα regulates genes involved in:

Mitochondrial biogenesis: PGC-1α, NRF-1, NRF-2, TFAM
Oxidative phosphorylation: Components of electron transport chain complexes I-V
Fatty acid oxidation: CPT1β, MCAD, LCAD, VLCAD
TCA cycle enzymes: SDH, IDH, MDH
Antioxidant defense: SOD2, catalase, GPX

ERRβ and ERRγ: These isoforms share significant sequence homology with ERRα and regulate overlapping but distinct sets of metabolic genes . ERRγ is particularly important in pancreatic β-cells and skeletal muscle, where it influences insulin secretion and glucose uptake .

SLU-PP-332 Selectivity Profile

SLU-PP-332 demonstrates high selectivity for ERR family receptors over other nuclear receptors. Key selectivity characteristics include:

Receptor	Activation by SLU-PP-332
ERRα	Potent agonist (EC₅₀ ~ 20-50 nM)
ERRβ	Potent agonist
ERRγ	Potent agonist
ERα (Estrogen Receptor α)	No significant activation
ERβ (Estrogen Receptor β)	No significant activation
PPARα	No significant activation
PPARγ	No significant activation

This selectivity profile makes SLU-PP-332 a valuable tool for dissecting ERR-specific effects from other nuclear receptor pathways .

Key Research Applications

Exercise Mimetic and Endurance Research

SLU-PP-332 has garnered significant attention as an exercise mimetic a compound capable of inducing the beneficial effects of exercise without physical training . This property makes it invaluable for studying the molecular pathways underlying exercise adaptation.

Key findings from preclinical studies include:

Increased Running Endurance: SLU-PP-332 treatment in mice resulted in significantly increased running distance and time to exhaustion compared to controls
Enhanced Oxidative Metabolism: Treated animals showed increased fatty acid oxidation and improved metabolic flexibility
Muscle Fiber Remodeling: The compound induced a shift toward oxidative muscle fibers, characteristic of endurance training. p s y c h e d e l i c g u i d e e x p l a i ned.
Mitochondrial Biogenesis: SLU-PP-332 increased mitochondrial density and function in skeletal muscle

Metabolic Disease Research

SLU-PP-332 has demonstrated significant effects in models of obesity and metabolic syndrome:

Weight Reduction: In diet-induced obese mice, SLU-PP-332 treatment significantly reduced body weight gain and fat mass
Improved Glucose Homeostasis: The compound improved insulin sensitivity and glucose tolerance
Enhanced Energy Expenditure: Treated animals showed increased whole-body energy expenditure and thermogenesis
Hepatic Steatosis Reduction: SLU-PP-332 reduced liver fat accumulation in obese models

Mitochondrial Function Studies

As a master regulator of mitochondrial biogenesis and function, SLU-PP-332 is widely used in mitochondrial research:

Mitochondrial Biogenesis: Investigate PGC-1α-dependent and independent pathways of mitochondrial formation
Oxidative Phosphorylation: Study regulation of electron transport chain components
Mitochondrial Dynamics: Examine effects on mitochondrial fusion, fission, and mitophagy
Mitochondrial Disease Models: Explore potential therapeutic applications for mitochondrial disorders

Cardiovascular Research

ERRα is highly expressed in cardiac tissue, where it regulates energy metabolism and contractile function. SLU-PP-332 is used to study:

Cardiac Metabolism: Investigate substrate utilization (fatty acids vs. glucose) in heart tissue
Cardiac Hypertrophy: Explore ERR signaling in pathological cardiac remodeling
Ischemia-Reperfusion Injury: Study metabolic adaptations during ischemic stress

Skeletal Muscle Research

SLU-PP-332 is extensively used in muscle biology research:

Fiber Type Specification: Investigate molecular mechanisms controlling slow-twitch vs. fast-twitch fiber determination
Muscle Wasting: Explore therapeutic approaches for sarcopenia and cachexia
Metabolic Flexibility: Study substrate switching between glucose and fatty acids in muscle tissue

Quality Assurance: Setting the Standard for Research Compounds

Manufacturing Excellence

Eupharmaceutical sources SLU-PP-332 from certified GMP facilities with rigorous quality control protocols:

HPLC Purity Analysis: ≥99% purity verified by high-performance liquid chromatography
Mass Spectrometry Verification: Molecular weight confirmation via LC-HRMS
Batch-Specific Certificates of Analysis: Complete documentation for each production run
Research-Use Only (RUO) Labeling: Full compliance with research compound regulations

Chemical and Product Specifications

Specification	Detail
Product Name	SLU-PP-332 Peptide (ERR Agonist)
CAS Number	2766700-43-8
Molecular Formula	C₂₅H₂₇ClN₄O₄
Molecular Weight	482.96 g/mol
Purity	≥99% (HPLC verified)
Appearance	White to off-white lyophilized powder
Form	Lyophilized powder
Solubility	Soluble in DMSO (≥10 mg/mL), limited water solubility
Target Receptors	ERRα, ERRβ, ERRγ
Storage (Lyophilized)	-20°C; protect from light and moisture
Storage (Reconstituted)	2-8°C for short-term; aliquot and store at -20°C for longer storage
Shelf Life	24 months from date of manufacture (lyophilized)
Intended Use	Research and laboratory use only
Documentation	Certificate of Analysis provided with each batch

Stability and Handling Guidelines

Lyophilized Powder Storage: Store lyophilized SLU-PP-332 powder at -20°C in a dry, dark environment, protected from light and moisture . Under proper storage conditions, the powder maintains stability for up to 24 months from the date of manufacture.

Reconstitution Protocol:

Allow vial and solvent to reach ambient temperature before opening to prevent condensation
Reconstitute using DMSO for stock solutions (≥10 mg/mL). For aqueous solutions, prepare in DMSO first, then dilute with appropriate buffer
Inject solvent slowly down the inside wall of the vial to minimize foaming
Gently swirl or roll the vial until fully dissolved—do not shake vigorously
Label the vial with the date of reconstitution
Refrigerate immediately at 2-8°C

Reconstituted Solution Storage: For short-term use, store at 2-8°C. For longer-term storage, aliquot into single-use portions and store at -20°C . Avoid repeated freeze-thaw cycles.

Protection from Light and Moisture:

Store in original packaging protected from light
Keep vials tightly sealed when not in use
Allow refrigerated vials to reach room temperature before opening to prevent condensation

Key Benefits

Premium Quality Manufacturing: GMP-certified production, ≥99% HPLC-verified purity with lot-specific COAs
Well-Characterized Mechanism: Potent and selective ERRα, ERRβ, and ERRγ agonist
Exercise Mimetic Properties: Induces endurance benefits without physical training in animal models
Metabolic Research: Enhances energy expenditure, fatty acid oxidation, and mitochondrial biogenesis
Obesity Research: Reduces body weight and fat mass in diet-induced obesity models
Glucose Homeostasis: Improves insulin sensitivity and glucose tolerance
Mitochondrial Function: Potent inducer of mitochondrial biogenesis through PGC-1α pathways
Skeletal Muscle Studies: Promotes oxidative fiber type specification and metabolic flexibility
Cardiovascular Research: Regulates cardiac metabolism and energy homeostasis
Selective ERR Agonist: No significant off-target activity at estrogen receptors or PPARs
In Vivo Active: Demonstrated efficacy in preclinical animal models
Well-Characterized: Published in high-impact journals including Science
Stable Formulation: 24-month shelf life under proper storage conditions
Comprehensive Documentation: Certificates of Analysis with batch-specific purity data
48-Hour EU & UK Delivery: Rapid shipping to research facilities across Europe
Batch Consistency: Rigorous quality control ensures lot-to-lot reproducibility
EU Sourced: Available from within the European Union. m a g i c m u s h r o o m s.

Frequently Asked Questions

Q: What is SLU-PP-332 and how does it work?

A: SLU-PP-332 is a synthetic small molecule agonist of the estrogen-related receptors (ERRα, ERRβ, and ERRγ) . It activates these nuclear receptors, which are master regulators of genes involved in mitochondrial biogenesis, fatty acid oxidation, and energy metabolism . In animal models, SLU-PP-332 has been shown to increase endurance and prevent weight gain in obese mice .

Q: What purity level can I expect when I buy SLU-PP-332 from Eupharmaceutical?

A: All SLU-PP-332 from Eupharmaceutical is tested to ≥99% purity by HPLC, with Certificates of Analysis provided with every order . Each batch is individually analyzed, ensuring you receive material suitable for rigorous research applications.

Q: What is the molecular weight and CAS number of SLU-PP-332?

A: SLU-PP-332 has a molecular weight of 482.96 g/mol and CAS number 2766700-43-8 . Its molecular formula is C₂₅H₂₇ClN₄O₄ .

Q: How should I store SLU-PP-332 for long-term stability?

A: Store lyophilized SLU-PP-332 powder at -20°C, protected from light and moisture . Under proper storage conditions, the powder maintains stability for up to 24 months. For short-term use, store reconstituted solution at 2-8°C; for longer-term storage, aliquot and store at -20°C .

Q: What is the solubility of SLU-PP-332?

A: SLU-PP-332 is soluble in DMSO at ≥10 mg/mL . It has limited water solubility; for aqueous applications, prepare stock solutions in DMSO and dilute with appropriate buffer .

Q: What research areas commonly use SLU-PP-332?

A: SLU-PP-332 is widely used in exercise mimetic and endurance research, metabolic disease studies, mitochondrial function research, cardiovascular research, and skeletal muscle biology studies .

Q: What is the mechanism of action of SLU-PP-332?

A: SLU-PP-332 is a selective agonist of ERRα, ERRβ, and ERRγ, with no significant activity at estrogen receptors or PPARs . Activation of these receptors induces expression of genes involved in oxidative metabolism, mitochondrial biogenesis, and fatty acid oxidation .

Q: Is SLU-PP-332 legal to purchase for research in the UK and EU?

A: SLU-PP-332 is an investigational compound not approved for human use by the MHRA in the UK or the EMA in the EU . It is sold strictly for research purposes only. The sale of unlicensed compounds under “research use only” labeling is permissible for legitimate research purposes when supplied to qualified buyers such as laboratories and research facilities. Be s t p syc h e d e l i c t h e r a p y e x p l a i n e d

Q: Do you ship SLU-PP-332 to EU countries?

A: Yes. As a dedicated EU peptide supplier, we ship SLU-PP-332 to all European Union member states with our guaranteed 48 hour delivery peptide service. Our EU fulfilment centre ensures rapid delivery without customs delays. All shipments use protective packaging to maintain compound integrity during transit.

Q: What documentation do you provide with SLU-PP-332 orders?

A: Every order includes a Certificate of Analysis (COA) with batch-specific purity data . Additional documentation, including HPLC chromatograms and mass spectrometry data, is available upon request for researchers requiring comprehensive analytical verification.

Q: Has SLU-PP-332 been studied in animal models?

A: Yes. A landmark study published in Science demonstrated that SLU-PP-332 treatment in obese mice significantly increased energy expenditure, enhanced fatty acid oxidation, and prevented weight gain . The compound also increased exercise capacity in animal models without physical training .

Q: Do you offer bulk quantities of SLU-PP-332 for institutional research?

A: Yes. We accommodate bulk orders for research institutions. Contact our team at contact@eupharmaceutical.com for volume pricing, custom requirements, and supply agreements for ongoing research programs.

Advance Your Research with SLU-PP-332 Peptide

Eupharmaceutical is your trusted source for SLU-PP-332 Peptide, the premium choice for researchers investigating exercise mimetic pathways, metabolic disorders, and mitochondrial function. With over a decade of research since its discovery, SLU-PP-332 has emerged as one of the most potent and selective ERR agonists available for the research community .

Whether you are exploring exercise mimetic mechanisms, designing metabolic studies, investigating mitochondrial biogenesis, or researching cardiovascular metabolism, our rigorously tested compound provides the quality and consistency your work demands.

Order today and experience the Eupharmaceutical difference – premium quality, rapid 48-hour delivery across the EU and UK, and expert support for the European research community.